Effects of environmental contaminants on cell-mediated immune mechanisms of the oyster
Principal Investigator:Robert S. Anderson
Start/End Year:1990 to 1991
Institution:Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science
The production of cytotoxic oxygen metabolites by oyster blood cells will be quantified by state-of-the-art assays measuring biochemical events associated with hemocyte-mediated destruction of pathogens. Hemocytes from oysters exposed to sub-lethal concentrations of model pollutants will also be studied to identify immunotoxicological responses. Our data will define mechanisms of disease resistance, as well as unique biomarker assays for chemical stress.