Science Serving Maryland's Coasts


Effects of environmental contaminants on cell-mediated immune mechanisms of the oyster

Principal Investigator: 

Robert S. Anderson

Start/End Year: 

1990 to 1991


Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science



The production of cytotoxic oxygen metabolites by oyster blood cells will be quantified by state-of-the-art assays measuring biochemical events associated with hemocyte-mediated destruction of pathogens. Hemocytes from oysters exposed to sub-lethal concentrations of model pollutants will also be studied to identify immunotoxicological responses. Our data will define mechanisms of disease resistance, as well as unique biomarker assays for chemical stress.